50-State Healthcare and Pharmaceutical Licensing Compliance Guide
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South Dakota Healthcare and Pharmaceutical Licensing

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Licensing requirements for South Dakota healthcare and pharmaceutical companies and individuals.

This page provides an overview of healthcare and pharmaceutical industry licensing in South Dakota for individuals and businesses. You will find state requirements, application fees, filing instructions, and more. For assistance with licensing, please contact us to learn about our software and managed license services.

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Company Licenses

South Dakota Healthcare and Pharmaceutical Company Licenses

South Dakota Controlled Substance Registration

Agency:South Dakota State Board of Pharmacy
Foreign Qualification is Prerequisite:No
Registered Agent (Special Agency) Required?No

Registration Renewal

Agency Fee:

Varies

Due:

Due in conjunction with the DEA Controlled Substance Registration renewal.

South Dakota Full-Time Pharmacy License

Agency:South Dakota State Board of Pharmacy
Registered Agent (Special Agency) Required?No

Initial Registration

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$200

Notarization Required?:Required

Registration Renewal

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$200

Due:

Annually by June 30.

Notarization Required?:Required

South Dakota Non-Resident Pharmacy License

Agency:South Dakota State Board of Pharmacy

Initial Registration

Form:

Nonresident Pharmacy Application / Renewal Form

Agency Fee:

$200

Notarization Required?:Required
Notes:
  • Payment methods – MasterCard, Visa or American Express ONLY. If you do not have a MasterCard, Visa, or American Express, purchase a MasterCard, Visa, or American Express gift card to complete the payment process. 
Before you Apply:
  • Current home state license, its equivalent, or a written explanation why one is not available. (A primary source verification does fulfill this requirement).
  • Most recent inspection conducted in the last 4 years by home state regulatory or other inspecting entity. If one is not available, upload an explanation why.
    • Documentation corrections for of all non-compliance noted in the inspection. 
  • DEA certificate (if dispensing controlled substances).
  • Notarized Pharmacist-in-Charge Affidavit
  • Notarized Supplemental Affidavit must be completed if pharmacist-in-charge is not sole owner of merchandise and fixtures.
  • A list of other state(s) licensed in.
  • A complete Description of Type of Pharmacy Practice, i.e. retail, hospital, compounding, central fill, central processing, etc. including a description of the prescription drugs and services provided to patients in South Dakota.
  • Court documents if regulatory question(s) answered yes.
    • `First regulatory question is: Has the pharmacist-in-charge, sole proprietor, any other managing officer, director, or member ever plead guilty, no contest, or received a suspended imposition of sentence for a felony or other criminal offense (excluding minor traffic violations) that was not been reported on the last renewal.
    • Second regulatory question is: Has the pharmacy been disciplined in the last four (4) years?
  • If a Power of Attorney (POA) granting signing authority is being used, upload that document along with form that is signed using the POA. 
  • List all registered tecnicians
  • List all pharmacists
  • List all pharmacy interns
  • If this location is requesting a waiver/exemption from reporting to the PDMP, provide the reason
  •  

Registration Renewal

Form:

Nonresident Pharmacy Application / Renewal Form

Agency Fee:

$200

Due:

Annually by June 30.

Notarization Required?:Required

South Dakota Part-Time Pharmacy License

Agency:South Dakota State Board of Pharmacy
Registered Agent (Special Agency) Required?No

Initial Registration

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$160

Notarization Required?:Required

Registration Renewal

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$160

Due:

Annually by June 30.

Notarization Required?:Required

South Dakota Remote Pharmacy (Telepharmacy) License

Agency:South Dakota State Board of Pharmacy

Initial Registration

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$200

Notarization Required?:Required

Registration Renewal

Form:

South Dakota Pharmacy Application / Renewal Form

Agency Fee:

$200

Due:

Annually by June 30.

Notarization Required?:Required

South Dakota Wholesale and Other Drug Distributors License

Agency:South Dakota State Board of Pharmacy

Initial Registration

Instructions:

New Application Instructions and User Manual - Wholesale or Other Drug Distributors and 503B Outsourcing Facilities

Filing Method:

Online

Agency Fee:

$250 for wholesalers and other distributors and $200 for 503B outsourcing facilities.

Registration Renewal

Instructions:

Renewal Application Instructions and User Manual - Wholesale or Other Drug Distributors and 503B Outsourcing Facilities

Filing Method:

Online

Agency Fee:

$250 for wholesalers and other distributors and $200 for 503B outsourcing facilities.

Due:

Annually by December 31.

Individual Licenses

South Dakota Individual Healthcare and Pharmaceutical Licenses

South Dakota Pharmacist License

Agency:South Dakota State Board of Pharmacy

Initial Registration

Form:

Registration by NAPLEX Examination

Agency Fee:

$35

Registration Renewal

Form:

Renewal Form

Agency Fee:

$125

Due:

Annually by September 30.

South Dakota Pharmacy Intern Certificate

Agency:South Dakota State Board of Pharmacy

Initial Registration

Form:

Application for Intern Certificate

Agency Fee:

$40

Registration Renewal

Filing Method:

Online

Agency Fee:

$40

Due:

Annually by October 1.

South Dakota Pharmacy Technician Registration

Agency:South Dakota State Board of Pharmacy

Registration Renewal

Form:

Technician Registration and Renewal Application & Instructions

Agency Fee:

$25

Due:

Annually by October 1.

Learn about healthcare and pharmaceutical licensing in other states:

Controlled Substance Registration - In addition to a pharmacy license, controlled substance registration registration is required in many states for pharmacies that distribute controlled substances.

NABP (National Association of Boards of Pharmacy) - Host a variety of programs and resources relating to pharmacist and pharmacy licensure and examination.

Pharmacist in Charge - A licensed pharmacist designated by a pharmacy to act as the party responsible for compliance with regulations.

VPP (Verified Pharmacy Program) - A program run by NABP that allows state boards to share information and more easily register out-of-state pharmacies.